ea0078oc4.4 | Oral Communications 4 | BSPED2021
Gunn Harriet
, Hallqvist Jenny
, Doykov Ivan
, Heywood Wendy
, Steinbeck Katharine
, Mills Kevin
Background and Methods: PCOS is common and associated with significant comorbidity. Yet, its pathogenesis is complex and poorly understood. We have developed new methods for deep phenotyping discovery proteomic profiling of urine to identify disease mechanisms and novel non-invasive biomarkers for PCOS in adolescents. We undertook proteomic analysis (nano 2D-LC-QTOF MSe) on a subset of 15 samples from a longitudinal PCOS cohort of 40 participants. We compared the ur...